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error downloading refseq for local BLAST install via FTP

I am having trouble downloading the refseq database required for BLAST+. I am following the instructions from http://www.ncbi.nlm.nih.gov/books/NBK52640/ but get No such file or Directory error using...

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Old Blastall Vs New Blastall

I've been using blast 2.2.15 for a while, and I recently downloaded blast 2.2.25 on my new computer. I wanted to test the new version of blastall with a lamprey genome database and sequence that works...

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Gene ID conversion and Pathway analysis after mosquito blast

Hi all I have got my blast result from mosquito Contigs Fasta format.  Sth like  query_name query_length accession_number 1059N_ae_contig_1 676 XM_001650645 1059N_ae_contig_5 563 XM_001650988...

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Downloading Fasta Files

i need to download about 40 complete genomes from ncbi and still filter out sequences between specified bps(like btn 1000bp to 3000bp) from the genomes separately. i need help on how to do that. i...

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Preview temporary outputfile blast

Hi, Is there a way to peek at blast temporary file? I would like to know what sequence is analyzed in order to foresee how long the program will take to finish. top command shows that it uses around 4...

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Sequence Blast Against Rfam Database

Hi All,I am using blastn to blast my data against tRNAs which is extracted from RFam database. Then I picked one match from the blast result to confirm it by directly searching my read in RFam online...

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Help With Formatdb And Blast All

I have my own database of sequences stored in MySQL. I convert this database into a blastable format using formatdb, code below:formatdb -p T -i db.fastaI then do the same with the query sequence and...

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Command to get BlastDB(Blast Database) information

Hi guys, I have a very simple question on how to get the information on the size of BLASTDB created using standalone BLAST. I have created several BLAST databases and now I need information on their...

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Blast Nucleotide Vs. Nucleotide, Plus-Minus Results Only

Hi Folks, I am interested in running a blastn search to search for complementary sequence (potential biological function) between two groups of sequences, (Query blasted against Reference) such that...

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Compare Two Protein Sequences Using Local Blast

Hi,I have been given a task to compare the all the protein sequences of a strain of campylobacter with a strain of E.coli. I would like to do this locally using Biopython and the inbuilt Blast tools....

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Running BLAST on huge files

Hello,I have quite a simple question.I have a huge file of 7 GB (approx. 43 million sequences). I want to blast my 1 sequence (1000 bp) against it. Is it possible to do it on a normal computer with 300...

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Error with database alias when running blastp

I have made a blast protein database with this command:./makeblastdb -in input.fsa -out prot.db -dbtype prot -hash_indexIt has generated 8 files as follows:prot.db.phd  prot.db.phi  prot.db.phr...

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Errors In A Bioperl Script, Please Help Me To Have A Check, Thanks In Advance!

Dear friends: I have a blast report, and want to extract following information for each result(query): the Query_name, hit_number, name and description of the hit(HSP) with the highest identity. my...

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How To Identify Proteins Present Only In Pathogens But Not In Non-Pathogens...

I used PSI-CD-HIT-2D to compare the proteome of pathogen A to pathogen B from the same genus at 30% identity. The matched protein sequences (homologs above 30% identity) are then compared again to...

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How To Concatenate Blast Results (M8) Via Setting Threshold Of Distance...

hi, dear guysI performance blastn (-m 8) using a query file of many sequences, and for each query sequence, the output contains many fragmental hits of significance. however, these hits have no...

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Can Biopython Parse Gzipped Xml From Blast?

I have been using blast+ with the xml output format (-m7 in the older days, and outfmt 5 with ncbi-blast+). Since the XML files are huge, I have been gzipping them. I have also been using Biopython to...

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From Blast To Ucsc Genome Browser: Valid Loci

Hello,BLAST, sometimes, does not propose direct links to Genbank pages as reports, and this leads to unaccepted entries in the UCSC Genome Browser's search term box. How could I avoid those results? Is...

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What is the best approach for predicting regulatory elements in the pig genome

Hi All,What is the best computational method for predicting regulatory elements in the pig genome? I have a list of differentially expressed genes as determined by RNA-Seq in 3 different tissues and I...

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Database Error When Running Blastn

Hello, as initially stated here, I am experiencing problems when I try to run the blastn command blastn -query myquery -db mydatabase.fasta.nhr.What I get is:BLAST Database error: No alias or index...

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Blast: Influence Of Database Filesize On Performance, And Purpose Of...

Obviously BLAST is going to have better on-average performance on a smaller database than on a larger database. But for a particular (large) database (let's say 10s of GB), how does splitting up the...

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