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How To Find Sequences With A Given Number Of Mismatches

Hi! Is there any script or tool that allows to find similar sequences given the maximum acceptable number of mismatches? What I want is something similar to a Blastn search, but instead of filtering...

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From Blast To Ucsc Genome Browser: Valid Loci

Hello,BLAST, sometimes, does not propose direct links to Genbank pages as reports, and this leads to unaccepted entries in the UCSC Genome Browser's search term box. How could I avoid those results? Is...

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How To Parse Psiblast Results Using Biopython And Blast-2.2.24+?

I'm trying to run a PSIBlast program which selects certain sequences out at every round before it does the next iteration. For this I need the Round attribute shown in...

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Ncbi C++ Exception: Ncbi::Cmemoryfilesegment::Cmemoryfilesegment() - File...

I have tried running a command line blast. The query file is a multi fasta file containing 2600 sequences. It was made a BLASTX against a proteins sequences (ProDom) of size 2 GB (prodom.phr : 1:00 GB,...

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FASTA-Reader: First data line in seq is about 100% ambiguous nucleotides...

I am not sure if this is a problem or if in fact the process is correct. Any help is much appreciated. I am trying to make blast databases from assembly fasta files, and have seeing the above error. It...

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Get Pairwise Sequence Identity

Hey,for some project I need to run pairwise sequence alignments (local ones, i.e. Smith-Waterman) on protein sequences in order to produce a similarity matrix based on the percentage of identical...

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Any tool to generate protein similarity matrix

Hi, I want to calculate the similarities between each protein pariwise and then implement random walk to predict interactions. A paper mentions "J. Mol. Biol. (1981) 147, 195-197" to compare two...

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Blastdbcheck Error

I keep getting errors on the following command:blastdbcheck -db nt.00Writing messages to <stdout> at verbosity (Summary) ISAM testing is ENABLED. Legacy testing is DISABLED. By default, testing...

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short protein BLAST

Dear AllI am performing BLAST.  The database is a collection of short protein sequences (~40 aa in length,  short but not short very much).  The query file contains short protein sequences as well (~40...

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E Values Using Blastp In Biopython

Is there a reason for the E Value to differ when using BLAST on the web and using BioPython? My understanding is that these are the same source, so I am unable to understand the following differences....

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Find The Rid For A Remote Blast+ Result

I ran a remote blastn search using the command line blast 2.2.25+ and got the results back in asn format. when I went to reformat the results using blast_formatter, I realized I needed the RID for my...

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blast -F F equivalent in blast+

In legacy blast there is an option -F, which turns on or off filtering. By default filtering is ON and it effects my results a lot, so I turn it off by -F F (false)In blast+ I couldn't figure out the...

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Protein Sequence Homology Score, Align Or Blast

Hi,I want to get homology scores for every pair of human proteins acoording to their sequence amino acid constitution. should I blast these pairs(blast2seq) or align these pairs(localAlignment)?

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Download Ensembl Blastn Result

Hi,How can I download blast results from ensembl. I blast 10 sequences against all ensembl species. Now I have the result page and I want to download all hits to compare them.Is it possible ?Here's the...

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Best Blast Hit Without Pain

Hi,This might be naive but here I go. I have a set of target sequences and a query sequence. I want to find the best BLAST hit (lets say using the bit score). The straightforward way to do this is to...

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Average nucleotide identity

Hi,I'm using ANI to determine if two bacteria species are related or not. What is the threshold for saying two sequences come from different species ?

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Problem Parsing Xml In Biopython

Hi mates, I m new in python and I m trying to parse a result from local Blast...here the code.from Bio.Blast.Applications import NcbiblastpCommandline from Bio.Blast import NCBIStandalone from...

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How To Generate A Species Distribution From Blast Xml Output

Hi,I am very new in bioinformatics field. I have a BLAST XML output file and I need to parse it to generate a species distribution. I was hoping someone could show me how it can be done by Biopython...

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Blast RNA nucleotide sequences with Protein-RNA complexes

Hi,I have two datasets - one folder containing nucleotide sequences of different only RNA proteins and the other folder containing different protein-RNA complexes (all FASTA files). I want to blast...

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Import Xml Blastx Results In Geneious

Hi,I have the xml results file of my local blastx and I would like to import the annotations directly on my sequence in geneious. Do you know if there is a way ?Thanks,Aurelien

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