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Obtaining A Maximum Number Of Blast Hits: Problem...

I am having trouble getting blast to give me "correct" results. I am trying to retrieve as many hits with e-value better than 1. I query the database with a sequence that should have several thousand...

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Standalone Blast In Bio Python Module

I've been trying to check sequence conservation of target genes with a uploaded database using local blast StandaloneBlast in python. The tutorial is very confusing, can anybody give me link to...

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Limit The Memory Size Of Blast?

Would anyone tell me whether it is possible to limit the memory size in blast+/blastall search? If possible, how should we do it? Thanks!

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Finding Protein Homology?

I'm looking for something that's more rigorous than BLAST and less rigorous than a global alignment-esque algorithm. Is there a paper out there that compare methods? What's the most popular method?I'm...

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Mpiblast Vs Blast+

How up-to-date is mpiBlast compared to blast+ from ncbi? I am not sure what the relation ship between mpiblast and blast+ is, is mpiBlast derived from blast+. blast+ seems to be multi-threaded, but I...

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How To Parse Psiblast Results Using Biopython And Blast-2.2.24+?

I'm trying to run a PSIBlast program which selects certain sequences out at every round before it does the next iteration. For this I need the Round attribute shown in...

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bioinformatics related problems

hello friendsi have downloaded blast database (rpsd; for conserved domain). but i am unable to us it. so plz can anyone tell me how i can use (untar files of cdd.tar.gz file).thanks:) 

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How do I generate the correct input files for Blast2GO from CuffLinks2 output?

Hi everyone,Sorry if this is a "no-brainer" type of question, I just started assembling my first transcriptome last week (and am having a really good time learning how to work with all these data!). I...

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Blastclust Output Problem.

HI,I have installed the blast standalone latest version 2.2.25 with the help of the installation guide http://www.ncbi.nlm.nih.gov/staff/tao/URLAPI/pc_setup.html. I ran the blast with a 14Mb fasta file...

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Blast Db Version

Hi all,I'm currently updating my BLAST application from the legacy BLAST to BLAST+. It seems that BLAST+ expects 'version 4' database files. Which my blast DB's apparently are not.Is there a way to use...

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Align Multikb Contigs Of A Mammalian Genome Against List Of Mammalian Genome...

I would like to be able to align multi-Kb contigs of a non-assembled mammalian genome against the list of available mammalian genomic assemblies. I would like to do this locally since I have got many...

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Disagreement When Computing Contig Alignments With Different Tools.

Hi everybody I need a small suggestion : After assembly of one listeria genome with "Spades" i want to plot reference genome with my contig file. So i am using Mauve and Quast 2.3 to plot . Now i am...

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Find All Similar Sequences In Genbank

Hi, I would like to get a feel for how many sequences related to my virus of interest are available on GenBank. I am thinking about using a recursive BLAST approach. Start with one genome, BLASTn, and...

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Is There Any Api Of Blast And Uniprot To Align Protein?

Given a set of protein's gi/UniProt identifiers. I want to find the e-value/identity between each of the pairs. I decided to do it by program but I cant find any apis of Blast and Uniprot. Any ideas?

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Makeblastdb Help

Hi,I feel I'm being really dumb here, so please excuse me! I have a file of fasta sequences which I want to make into a blast databse for standalone blast.I haev the fasta file saved in the bin folder...

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I Use Blastdbcmd Command With Nr Database And It Gives Me The "Not Found...

This is the errorBLAST Database error: No alias or index file found for nucleotide database [nr] in search path [/home/aj3/Desktop/h/database::]what should I do? do I have to use any other commands...

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Retrieving Protein Structures

I want to make structural analysis of lysosomal proteins found in mammals. To make start, I would like to retrieve as many structures as possible from the biological database (PDB). These structures...

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Parsing Blast Results For Different Genus

Dear All,I have obtained several .gb BLAST results that I want to split in different .gb or .fasta files accordingly to genus.I searched for different ways to do it in the web, but didn't find a way to...

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Different blast results between CLCBio and local blast

Hi,I've been using CLCBio to blast assembled contigs, but it's really slow. I decided to try setting up a local blast database and using that to blast my contigs, but I'm getting different results even...

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Obtaining the top matches from blast

Hi,I have downloaded the current version of the stand-alone-blast (ncbi-blast-2.2.29+) and I am trying to use blast (blastn) to find similarity of of a group of nucleotide sequences that I have....

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