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Best Blast Hit Without Pain

Hi,This might be naive but here I go. I have a set of target sequences and a query sequence. I want to find the best BLAST hit (lets say using the bit score). The straightforward way to do this is to...

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Mapping blast xml report elements to their variable names in biopython

Hi all ^_^ Im working on a script in biopython that extracts SSR's from some plant species , blast their sequences against each other and group the results of similarity based on some coverage value ....

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Blast more thn several DNA sequences

 Can we blast several DNA sequences against whole genome simultaneously? If yes, thn How?

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How To Get Conservation Of Vaccine Candidates Between Hundreds Of Bacterial...

Hi community,We have identified vaccine candidates via an ex-vivo RNA-seq approach. Next step would be to perform conservation of these candidates (about 20) between multiple bacterial strains (about...

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In biopython, how can i get the 100% identity aligment?

I find the way to get the identity of hsp ,but no alignment.One alignment can have multiple hsp, that means the score(identity) of hsp is no equal to alignment. when i do blast in webpage, i always get...

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Annotating Rna-Seq Data Using A Reference Genome.

I have RNA-seq reads from a non-model organism. I used cufflinks to identify transcripts. Is there an existing pipeline to BLAST these transcripts to a model organism's proteins to identify orthologs?

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Standalone Blast Options

Hi all , I'm using local BLAST to retreive the single top most hit invoking "-v" option of blastall/RPSBLAST, from the local database sequences. I'm getting the top hit in most of the cases but in some...

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Can't access individual attributes of tabular outfmt 6 blast output while...

Hi ... I'm trying to parse a blast tabular format file (outfmt 6) to access it's individual elements for further manipulation . I need to retrieve the qseqid, qstart, qend, qlen, qseq, sseqid, sstart,...

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Getting Taxonomy Lineage From Ncbi Gi Or Accession Number

Hey GuysI have a specific question about getting a taxonomic lineage, given a NCBI accession or GI number. I have in the past used the module from CPAN (below) but I belv it only works for GI's and not...

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Genomic Sequences For Drosophila In Refseq

Pscan was recommended to do TF enrichment previously. RefSeq (for human, mouse, and drosophila, e.g. NM_000546) in one of the acceptable identifiers. I have a list of genes in a non-model organism, and...

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Quick Command To Split Large Blastx Files?

Any thoughts? I have large 7 gb files as resulted from Blastx any clue how to split them?Edit:These are standard blastX files (fasta). I need to split them for a program (binning) call SOrt-ITEMS/MEGAN

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RNA-seq for ncRNA analysis in Rice

Could anyone kindly suggest some protocols on analyzing ncRNA using RNA-seq data, articles published on identifying and analyzing Plants ncRNA will be equally of great help.Thanks 

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How Can Different 3 Reading Frames Have Similarity For The Same Sequence...

Hi, I have a DNA sequence ( it's about 388 bp), which I am comparing with GenBank sequences using Blastx. I understand that Blastx looks into all possible 6 reading frames when translating a DNA seq,...

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Webtool For Fetching Pmids From Blast?

Hi, I was wondering if there is a web service that extracts all of the PMIDs that are in the results for a BLAST search? Example: I input the sequence for enchanced FLP and get a list of all the PMIDs...

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Get Pairwise Sequence Identity

Hey,for some project I need to run pairwise sequence alignments (local ones, i.e. Smith-Waterman) on protein sequences in order to produce a similarity matrix based on the percentage of identical...

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Using Ncbi-Blast-2.2.25+ Remote Flag. Where Can I Find The List Of Databases...

Hello.I am trying to blast using -remote flag to use the databases on the remote server. The problem is I don't know the name of the datbases for the -db flag. Is there any website where I can get the...

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Blast+ Error: Sequence Not Returned

I'm getting an error when running blastn against the nt database:Error: (117.2) CThread::Wrapper: CThread::Main() failed NCBI C++ Exception: Error: (CSeqDBException::eArgErr) Sequence not returned.The...

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How To Filter A Blast Xml Output ?

Hello list, I have very large xml blast outputs (in order to use with blast2go) and I need to reduce these consequently according to a selected criterium (for instance the E-value). Did anybody write a...

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Bl2Seq/Blastall And The E Value Help

I am using bl2seq(2.2.25) to blastn two fasta files. I am not sure I fully understand how the (-e) parameter works. I thought the -e parameter was a cut off e-value and would therefore show all results...

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putative conserved domain in introns

I am currently working on set of long intron sequences..once I put them in to NCBI CD-search tool(CDD) those intron sequences showed that such sequences are having putative conserved domains and the...

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