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short protein BLAST

Dear AllI am performing BLAST.  The database is a collection of short protein sequences (~40 aa in length,  short but not short very much).  The query file contains short protein sequences as well (~40...

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Converting ANY blast output file to an alignment fasta file.

Hey there guys.  We use the Blast Command Line toolkit to Blast populations against each other. We created a database of transcriptomes of one population and then used the blast command line kit to...

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Blast - problem with xml output

I encountered a weird problem when I used blast(i'm using blastall 2.2.26). I have a fasta file with 8 sequences and I'm running blast on it to get the xml output, the problem is I get 1-8 iterations...

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Blast+ Query Splitting/Chopping In Blastxml Format

What's the easiest way to split a BLAST+ query into pieces BLAST+ all of the chunks with blastn against NT, and merge them back together? I presume using query_loc is better than literally splitting...

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What does sframe signify in BLAST output?

Hi,I am relatively new to the field of Bioinformatics and have just been introduced to BLAST. I'm trying to understand the output available from the BLAST program. As listed in the NCBI manual, I am...

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Alignments As Queries In Blast

Hi guys, i'm reading a paper and i'm not understanding the following note:Alignments were made using IGRs (intergenic regions) from S. meliloti as queries in BLAST comparisons against the...

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Running Blastp With Taxid

Using Ubuntu 12.10 and the blastp command from the ncbi-blast+ package from the official repos, I want to query the remote ncbi database. So far, my command line looky like$ blastp -db nr -query...

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Taxonomy Of Blast Hits

Lets have 200k genomic contigs with some (unknown) bacterial contamination. I blasted (blastn vs nr) all of them, got tabulated output and passed the uniq acc nos ca 5k to Batch Entrez. Since neither...

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Python Program Accepting Fasta And Blast, Outputting In Xml Then Returning...

Ok. The assignment was to write a program which accepts an input argument of a FASTA file and prints the hit_id of all found sequences using three functions: run_blast (accepting the FASTA and optional...

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Downstream Analysis Of Assembled Transcripts (Cufflinks, Trinity)

Are there any good available programs/scripts for analyzing assembled transcripts? I imagine something like a script to blastn, blastx and tblastx each transcript and report the best hit. Something...

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Is There Such A Way/ Program To Do This...

Hi guys,I followed the Trinity/ RSEM/ EdgeR pipeline and have produced some FPKM spreadsheets for genes and isoforms.I am currently analysing the isoforms:I have 3 sample conditions and I am comparing...

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Local Mirror Of Biological Databases

I'd like to set up a local mirror of certain large databases like the nt BLAST database, interpro etc.The biomirror project looks like a good candidate, but they seem to advocate using GridFTP, and...

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BLAST search against the genome

Dear all,I apologize for asking a very basic question.Using local BLAST searches against a genome, I am trying to retrieve full length homologous sequences of a gene of interest. Ultimately, I am...

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Distribution of e-values in Best Reciprocal Blast Hits for Ortholog Mining

Does anyone have an idea of how the distribution of expect values will look when using reciprocal blast to detect orthologs?

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Raw Alignment Score Calculation

Thanks for lots of answers and I've started with lots of sources here. It helps me to get a good introduction to blast.After I've now a little more understanding I can ask more specific questions such...

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Blastall gives several hits to the same subject sequence

Short query sequences will sometimes give several hits to the same (often large) subject sequence. This is problematic if you ask for the 20 best hits since blastall will actually give you the best...

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Find The Rid For A Remote Blast+ Result

I ran a remote blastn search using the command line blast 2.2.25+ and got the results back in asn format. when I went to reformat the results using blast_formatter, I realized I needed the RID for my...

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how to find different gene loci between two strains

I already have two complete genome,I want compare them to find different gene loci and related proteins.how can I do that?I read some papers about this,one said use blastp and then COGs,but I don`t...

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Select Sequence From A Psiblast, And Launch A New Iteration From It

I would like on my local machine or remotely if it is possible too, launch a psiblast from a sequence. Then, like on the website of ncbi, select my own sequences from the result file. And launch...

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Get Blast Database Size

I have piped unknown length sequences into makeblastdb. Now I want to know total length of those sequences (BLAST database size).Example: # "cat" is used as an example # My "real" sequences are piped...

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