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Running Blast With C

I'm trying to improve the parallelization of something and it is beneficial to not use system calls to start blast runs. It seems NCBI only has documentation for doing this in a C++ environment, but...

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Comparing Bowtie H_Sapiens_Asm Blastn -Task Blastn-Short -Db Human_Genomic

I am thinking the current supplied (pre-formatted) blastn humangenomic database from NCBI contains many many duplications of the same sequences. Is this correct? I think I only need the current...

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Quick Command To Split Large Blastx Files?

Any thoughts? I have large 7 gb files as resulted from Blastx any clue how to split them?Edit:These are standard blastX files (fasta). I need to split them for a program (binning) call SOrt-ITEMS/MEGAN

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Finding Pdb Codes Of Sequences Homologous To An Input Sequences

I need to write a script that can do a blastp with an input xml file, then find and display the PDB codes of sequences that are homologous. The definition I'm using for homology is: 1. the HSP in the...

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Scientific Names In Blast Output And Databases

Hi, I'm interested in getting the scientific names of my blast hits ran locally. I see blast+ search apps have option -outfmt which can take sscinames(seems new in version Blast+ 2.2.28), but even...

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Blast Results: Xml Tags Explained ?

Hi there,I would like to know if there is any description of the tags that are found in the XML file generated by blastall. I just cannot find any comprehensive document on the web .More precisely, I...

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How To Get Ungapped Sequences From Blast Output?

I am interested in getting ungapped sequence hits (hspsnogap) from blast output, I tried using this:result_handle = NCBIWWW.qblast("blastp", "nr", record.format("fasta"),expect=10,"hsps_no_gap")...

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Blast Nucleotide Vs. Nucleotide, Plus-Minus Results Only

Hi Folks, I am interested in running a blastn search to search for complementary sequence (potential biological function) between two groups of sequences, (Query blasted against Reference) such that...

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Blastx For A Million Metagenomic Sequences

I intend to use a similarity based binning program like MEGAN or SOrt-ITEMS or CARMA for analyzing sequences in my metagenomic data set. For this, I first have to generate a BLASTx output of my...

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Blast/Reblast To Verify Homologies

Hi!I am an informatics student from Germany attending a practical course on bioinformatics. I am new to the field of bioinformatics but I am willing to learn a lot. My first task is the following: I...

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Standalone Blast Issue

Dear all,I have recently installed blast-2.2.26 on my machine (running MacOS 10.7.3) and I tried to perform a BLAST search using a single protein sequence as query and a formatted (by me) database...

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blast against genomes in biopython

from Bio import Entrez, SeqIO from Bio.Blast import NCBIXML from Bio.Blast import NCBIWWW result_handle = NCBIWWW.qblast("blastn","nr",...

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Blast+ Error Code=12

Something really bizarre is going on. I ran 6 tblastn jobs independently using the following command line entry: tblastn -query blastqueries14920.fasta -out blastqueries14920.fasta.out -db...

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Blast more thn several DNA sequences

 Can we blast several DNA sequences against whole genome simultaneously? If yes, thn How?

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Blast output query

I did a local standalone blast pre-miRNAs against a genome in tabular format (-m 8) and got the results. My next steps for refining the results include GC content analysis, RepeatMasker etc. I am...

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Blast Multifasta Against Ncbi Nr Database, And Download All The Results

Hello, i have a fasta file with 7600 nucleotide sequences, i have a local nr database formated for blast, with makeblastdb, i don't use formatdb because it give errors (zero length sequences). I blast...

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ncbi-blast+ ThrowNullPointerException() when running inside a Docker container

NCBI blast+ seems to have trouble parsing some fasta files when running inside a Docker container. Note that I don't see the error when running blast outside the container. I'm using the sample input...

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How To Generate Blast Database

Hello I downloaded some database in gemnomes/Bacteria ( ftp://ftp.ncbi.nlm.nih.gov/genomes/Bacteria/Acetobacterium_woodii_DSM_1030_uid88073/ ) I want to use blast program. I have some problem. How can...

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Why is pre formatted refseq database larger than nt database in blastdb?

I went to the blast ftp database ftp://ftp.ncbi.nlm.nih.gov/blast/db/, there are 18 nt files, each is less than 800 MB, and for refseq_genome it has 83 files, most of which are larger than 800 MB,...

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Ncbi Refseq Viral Genomes

I want to create custom blastdb with all viruses available in the refseq. But I don't know which source files to use. My first point is:ftp://ftp.ncbi.nih.gov/genomes/Viruses/From research I concluded...

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