Gene Function through sequence homology

Hi

So I've got  list of genes putatively involved in Leptospira virulence, and I want to produce hypotheses on their function through sequence homology. So I was thinking of BLASTing them as a first step, but I'm not to sure how I would interpret the results. Are there better ways of going about this ? Any sort of resources that would help a beginner out with this task ? 

Thanks in advance :)